I think the biggest suggestion I have is to always be networking. It has made my situation much easier because I knew several people in the practice area I focus on and when I ended up without a job I didn't have to go try to convince them that I was only a victim of a bad economy (rather than fired for being a lousy lawyer). Also, keep in touch with those contacts. Don't be afraid to call them and tell them what happened - they're all going to figure it out on their own anyway. And the best jobs are never posted - you just have to know the right person at the right time.
I would also say that being laid off is an excellent time to reevaluate things, so people should really take advantage of it. It's amazing how you can really enjoy life while spending less money, for example. Or how you may find out that your job really was making you miserable but you didn't have enough distance to see that before. Someone told me once that you need to decide what kind of life you want and then find a job that gives you that kind of life. So often we find a job we want and then force our lives to work with it (especially if you went to law school right out of undergrad and really had no idea what you wanted out of life to begin with)... a little time away from work might show some people that they'd be much better suited to doing something completely different.